By Justine Burley, John Harris
The crowning glory of the human genome undertaking in 2000 dramatically emphasised the upcoming good fortune of the genetic revolution. the moral and social effects of this medical improvement are vast. From human copy to life-extending remedies, from the effect on gender and race to public health and wellbeing and public defense, there's scarcely part of our lives left unaffected through the impression of the recent genetics. A significant other to Genethics is the 1st giant research of the multifaceted dimensions of the genetic revolution and its philosophical, moral, social, and political value. It brings jointly the simplest and so much influential modern writing approximately genethics. Newly commissioned essays from well-known figures within the present debate supply a wide-ranging and interesting scholarly research of all of the matters that come up from this explosive technology.
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References and Further Reading Bjornson, R. L. et al. (1999), ``Turning Brain into Blood: A Hematopoietic Fate Adopted by Adult Neural Stem Cells In Vivo,'' Science 283, pp. 534±7. Kempermann, G. and Gage, F. H. (1999), ``New Nerve Cells for the Adult Brain,'' Scientific American 280, pp. 48±53. Svendsen, C. N. and Smith, A. G. (1999), ``New Prospects for Human Stem-cell Therapy in the Nervous System,'' Trends in Neuroscience 8, pp. 357±64. Svendsen, C. N. et al. (1999), ``Human Neural Stem Cells: Isolation, Expansion and Transplantation,'' Brain Pathology 9, pp.
Our society already makes decisions about whether to proceed with human clinical experimentation, in the absence of an absolute certainty about the trials' outcomes. Clinical trials are subdivided into phase I, II, III, and IV trials. Clinical trials start as phase I trials, which are essentially toxicity trials. The aim is to see whether, in moving a new experimental treatment from animals to humans, unforeseen toxicity will occur. As a matter of fact, phase I clinical trials of anticancer agents are dose escalation studies in which the new drugs' dose is increased until any specific toxicity appears.
Or would they simply feel as if they had been born into an old body? This same argument could be applied when considering using neural cell therapy to restore memory loss and cognitive decline seen in normal aging. In a way this problem touches on the complex issue of what ``self '' is, or perhaps, depending on definitions, consciousness (see Carol Rovane's chapter 18). Are we simply a collection of neurons organized in a specific way, or is there a grander plan to things, which only arises during the mystery of development, among the millions of dividing cells in the brain.