By Jae Y. Ro MD PhD, David J. Grignon MD, Alberto G. Ayala MD
This most modern quantity within the Atlases in Diagnostic Surgical Pathology sequence allows the identity of ailments of the male genitourinary tract. Lavishly illustrates a large variety of universal and strange stipulations affecting the prostate, seminal vesicles, testes, penis, and scrotum. additionally contains illustrations of complementary histochemical and immunohistochemical reports the place applicable.
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Extra info for Atlas of surgical pathology of the male reproductive tract
Figure 3-16. Prostalic inlraepithe lial neoplasia. Detail of lhe ind ivid ual cells making up lhis fla! pa llem of high-grade PIN. Figure 3-17. Prostatic inlraepilhelial neoplasia. Large gland involved by high-grade PIN producing a cribriform pallern. NOle lhe presence of concreli ons within the invo lved gland. There is also an infil tralive adenocarcinoma (O leason grade 3) in lhe surrounding fibrous stroma . Figure 3-111. Prostatic inlraepilhelial neopla sia. Detail of lhe cellular compos ilion from an area of a cribrifonn pallern of high-grade PIN .
Delai l of ¡he ce ll ular co mponen l of nodular hyperp lasia. NOle Ihe inward fol din g of lhe SlfOma producing a papillary arch ileclure and rhe presence 01' a double ce ll layer. BENIGN CO NDITI ONS • 31 Basal Cell HyperpÚlSio. S PECIAL S TA I NS AND I MM UNOH ISTOCH EMISTRY CUN ICAL o • Almost always seen as part of nodul ar prostatic hyperpla~i a (BPH) • ObSlructi ve symptoms or asy mptomatic • Usually encountered in tra nsurethral resec tions (transiti on zone) o o The lumen may contain acidic mucin (aleian blue- and mucicarmine-pos iti ve) .
MrCRosCOPIC Dr FFERENTlAL DI AGNOS IS • Four basic patterns: simple (Jobular), cystic, sclerotic, and postatrophic hyperplasia. • Simple (Iobular) atrophy: sma ll uniform glands, lined by tlnttened cells with scant cy toplasm, arranged in a lobu lar pattern around a central duct. Nuclei are hyperchromatic and nucl eoli are gene rally inconspicuous. Identifying a double cell layer is often difficult because of flattening of the epithelium. • Cystic atrophy : similar except the acini surrounding the central duct become cystically dil ated.